Shottie Loadout

For thos of you that use a shotgun as a primary defense, do you vary your load out?  I know some people at least entertain the idea.  I am leery of the wisdom of doing so.

For instance "I load rock salt first in case I wanna firing a warning shot, then I have a magnesium loaded shell to blind the home invaders like a flash band grenade.  I close my eyes for this one.  The next 2 are 00 buckshot for the bad guys, and then a slug round, if I have to crash through a locked door but it will work on a bad guy too.  The last 2 are 000 buck cuz I figure they are already pretty messed up and no need for overkill..."

Ok that was a bit of Mall Ninja fantasy, and not serious.  But there are valid argument for varying.  Like shot-slug-shot-slug.  Does anyone actually do that? 

I'd use 00 buckshot for everything.  Keeping track of what is next in thetube is more than my adrenalin addled brain can probably keep track of.  I know others would go all slug.  Still others would have birdshot in the first one, but only because they use the shottie to take out rattlesnakes in the yard.  For social purposes they might not count on #9 size shotgun pellets, but snakes would be in a bad way with that.